BCGitis: A rare complication after intravesical BCG therapy

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BCGitis: A rare complication after intravesical BCG therapy

In most cases, bladder carcinoma is located superficially, and the therapeutic approach is usually transurethral resection followed by intravesical therapy (chemotherapy or immunotherapy).(1,2) Initially produced as a vaccine against tuberculosis, BCG—an attenuated strain of Mycobacterium bovis—has been widely used in immunotherapy over the last decades.(1,3) Although BCG, used as immunotherapy...

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[Granuloma of epididymis of patient treated with intravesical BCG therapy--complication of BCG therapy or tuberculosis?].

We present a case of 72-year old man treated from 2007 for superficial bladder carcinoma. Patient had undergone surgical intervention for transitional cell carcinoma of the bladder, followed by BCG therapy. Two years later enlarged right testis and epididymis was observed. A resection was carried out. Histologic examination revealed in epididymis cauda granulomatous infiltration with eosinophil...

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704Mycobacterium bovis vertebral osteomyelitis due to intravesical Bacillus Calmette-Guérin (BCG): A rare complication of a common therapy

Background. Intravesical Bacillus Calmette-Guérin (BCG) is a well known and effective therapy for bladder carcinoma. Complications from BCG are very uncommon. Vertebral osteomyelitis secondary to BCG is exceedingly rare. Methods. We report a case of vertebral osteomyelitis due to Mycobacterium bovis following intravesical BCG therapy. We then present a review of all the reported cases of BCG-in...

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Mycobacterium bovis BCG vertebral osteomyelitis after intravesical BCG therapy, diagnosed by PCR-based genomic deletion analysis.

We report a case of Mycobacterium bovis BCG vertebral osteomyelitis 1.8 years after intravesical BCG therapy for bladder cancer. We differentiated BCG from other Mycobacterium tuberculosis complex members by PCR analysis of deletion regions and started an appropriate chemotherapy regimen resulting in the remission of symptoms within 1 month.

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Chest wall abscess due to Mycobacterium bovis BCG after intravesical BCG therapy.

We report a case of chest wall abscess caused by Mycobacterium bovis BCG that arose as a complication 1 year after intravesical BCG instillation. We identified M. bovis BCG Tokyo 172 in the abscess by PCR-based typing of Mycobacterium tuberculosis complex and analysis of variable number of tandem repeats data.

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ژورنال

عنوان ژورنال: Jornal Brasileiro de Pneumologia

سال: 2015

ISSN: 1806-3713

DOI: 10.1590/s1806-37132015000000126